The Houston Texans will face a rookie quarterback for the second time this season when they visit the New England Patriots during the Week 6 NFL schedule. Houston shut down Bears rookie quarterback Caleb Williams in Week 2, but he finished with just 174 passing yards and two interceptions while being sacked seven times. New England is giving No. 3 overall draft pick Drake Maye the chance to make his first career start, and the Texans are 6.5-point road favorites in Week 6 NFL odds. Houston is 0-7 all time on the road against the Patriots, but should we favor New England for coverage in our Week 6 NFL predictions?
Other matchups on Sunday include the Ravens (-6.5, 51.5) vs. the Commanders and the Cowboys (+3, 52.5) vs. the Lions. There are six teams with a Week 6 NFL spread of three points or less, but Philadelphia (vs. Cleveland) is the only team with a Week 6 NFL line favored by more than a touchdown. Before you make your Week 6 NFL picks, check out the NFL for spread, over-under and moneyline predictions powered by self-learning SportsLine AI.
AI predictions and AI ratings built by SportsLine’s data science team using cutting-edge artificial intelligence and machine learning techniques are generated for each game. AI predictions are determined by statistically learning from each team’s past data and quantitatively evaluating the strength of the opponent’s defense using a value out of 100 called a matchup score.
Once a prediction is made, the prediction, matchup score, and market odds are used to generate an AI rating. For example, if a team’s defense is poor, the team’s projections are off the line, and the odds are in their favor, you might see an A grade on an over bet.
Additionally, SportsLine AI is SportsLine’s first fully automated predictive model. Continuously updated with the latest available data to help identify the largest discrepancies in your rows. SportsLine’s AI PickBot had 128 4-star or higher picks this season and a whopping 1,674 4.5-star and 5-star prop picks last season. Anyone who follows it has improved considerably.
For Week 6 of NFL Betting, AI PickBot evaluated NFL odds and provided NFL betting predictions for all 14 games. Here you can only see AI predictions for the Week 6 NFL schedule.
NFL AI Top Picks Week 6
After analyzing every game in Week 6, AI PickBot reported that the Broncos covered a three-point deficit at home against the Chargers in a game with the lowest over-under of 35.5 that week. Mile High hasn’t been an attractive location for the Chargers over the past decade, losing seven of their last 10 games in Denver. They have lost two straight and haven’t scored a second-half touchdown since Week 1.
It will be difficult for Los Angeles to get back on track against a Denver defense that is allowing the second fewest points per game (14.6) in the NFL. Broncos rookie quarterback Bo Nix has not thrown an interception during the team’s three-game winning streak, and Denver has won the last three times the Chargers have been road favorites in this rivalry. AI PickBot predicts another outright win for the Broncos, showing there’s a lot of value for a team that’s an underdog at home. Check out more Week 6 soccer predictions and soccer picks on SportsLine.
How to make NFL picks for Week 6
Additionally, AI PickBot generated 14 other A-rated picks in week 6, including two with the coveted A+ grade. Before you place your own Week 6 NFL bets, you should check out AI PickBot’s NFL picks. You can only see it on Sportsline.
Who will win and cover each NFL game in Week 6? Which A+ players should you target now? Visit SportsLine now to see the NFL’s top picks against the spread, over-under, and on-money lines Let’s check the nomination. All of this comes from the latest SportsLine AI PickBot, which has 128 top-rated picks this season.
